Symbol
Name
ID

Cyba
cytochrome b-245, alpha polypeptide
MGI:1316658

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes

Abnormality of neutrophils

Impaired oxidative burst

Granulomatosis

Sinusitis

Lymphadenitis

Lymphadenopathy

Mediastinal lymphadenopathy

Splenomegaly

Rectal abscess

Liver abscess

Otitis media

Inflammatory abnormality of the eye

Eczematoid dermatitis

Recurrent bacterial skin infections

Discoid lupus rash

Osteomyelitis

Recurrent pneumonia

Absence of bactericidal oxidative respiratory burst in phagocytes

Immunodeficiency

Asthma

Sepsis

Recurrent Burkholderia cepacia infections

Recurrent E. coli infections

Recurrent Klebsiella infections

Recurrent Serratia marcescens infections

Recurrent Staphylococcus aureus infections

Recurrent Aspergillus infections

Recurrent respiratory infections

Meningitis

Cellulitis

Disease(s) Associated with CYBA

asthma

autosomal recessive chronic granulomatous disease 4

chronic granulomatous disease

Mouse Phenotypes		increased leukocyte cell number	abnormal neutrophil physiology	abnormal T cell activation	decreased inflammatory response	increased inflammatory response	lung inflammation	increased susceptibility to bacterial infection	sepsis
Availability	Mouse Genotype	increased leukocyte cell number	abnormal neutrophil physiology	abnormal T cell activation	decreased inflammatory response	increased inflammatory response	lung inflammation	increased susceptibility to bacterial infection	sepsis
	Cyba^nmf333/Cyba^nmf333
	Cyba^{tm1a(EUCOMM)Wtsi}/Cyba^{tm1a(EUCOMM)Wtsi}
	Cyba^tm1Dgh/Cyba^tm1Dgh (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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